Relief Effect of Bevacizumab on Severe Edema Induced by Re-irradiation in Brain Tumor Patients
نویسندگان
چکیده
IntroductIon Brain edema is a serious clinical event and could cause various neurological symptoms such as dizziness and headache. Drugs frequently used to relieve brain edema include steroid, dehydrant (e.g., mannitol), and diuretics. But the effects of these drugs were limited in patients with severe edema. Bevacizumab has been applied in the treatment of cerebral radiation necrosis.[1] Case studies have reported on the application of bevacizumab in the treatment of severe brain edema.[2] In the present study, we describe significant effects of bevacizumab on severe brain edema in patients with re‐irradiation.
منابع مشابه
Outcomes of Intravitreal bevacizumab in patients with acute branch retinal vein occlusion
Introduction: The study aimed to evaluate the long-term effects of intravitreal bevacizumab on macular edema and visual acuity in patients with Acute branch Retinal Vein Occlusion (BRVO) that had not received any treatment. Methods: 22 patients in first week of BRVO onset that was diagnosed with flurcein angiography were treated with intravitreal injection of 1.25 mg bevacizumab. Macular thicke...
متن کاملRole of bevacizumab therapy in the management of glioblastoma
Glioblastoma is one of the most common primary brain tumors and one of the most difficult to treat. In population-based studies only 30% of patients will survive 1 year and in the most efficacious surgery, irradiation, and chemotherapy clinical trials approximately 20% will live 2 years. Bevacizumab is a recombinant, antivascular epidermal growth factor receptor (VEGF) monoclonal antibody with ...
متن کاملA Small Meningioma with Extensive Peritumoral Brain Edema: A Case Report
Meningioma is the second most common brain tumor. The extent of peritumoral brain edema (PTBE) is one of the important prognostic factors in patients with meningioma.A 55-year-old female patient suffering from a progressive severe headache and mild left hemiparesis was referred to the Department of Neurosurgery, Rasool Akram Hospital (Tehran, Iran). The preoperative imaging revealed a 2×2 cm so...
متن کاملNeuroprotective Effects of Allicin on Neurological Scores, Blood Brain Barrier Permeability and Brain Edema Following Severe Traumatic Brain Injury in Male Rats: A Behavioral, Biochemical and Histological Study
Background and purpose: Allicin has a wide range of pharmacological functions, all of which can be demonstrated in anti-inflammatory, antioxidant, antifungal and anti-tumor activities. In this research, we investigated the neuroprotective role of allicin in the process of diffuse traumatic brain injury and its effect on interleukin levels and histological changes in rats. Materials and method...
متن کاملThe effect of curcumin in the recovery of severe traumatic brain injury: a double-blind randomized controlled trial
Background: Traumatic brain injury is one of the most important causes of death in trauma patients among the different types of trauma worldwide. In this study, the effect of curcumin on the outcome of severe traumatic brain injury,. Methods: This was a double-blind and paralleled randomized controlled study that was conducted on 128 patients aged 18 to 70 with severe brain trauma. Patients we...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره 128 شماره
صفحات -
تاریخ انتشار 2015